Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 207-366) antibody

Catalog No. ABIN1742306

The Rabbit Polyclonal anti- antibody has been validated for WB, ICC and IHC. It is suitable to detect in samples from Rat and Mouse. There is 1 publication available.

Quick Overview for Regulating Synaptic Membrane Exocytosis 1 (RIMS1) (AA 207-366) antibody (ABIN1742306)

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 207-366

Specificity: Specific for RIM 1

Cross-Reactivity (Details): no cross reactivity to RIM 2.

Purification: Affinity purified with the immunogen.

Immunogen: Recombinant protein (aa 207-366) of rat RIM 1, a stretch of divergent aa connecting the Rab binding motif and the PDZ domain.

Application Details

Application Notes: WB: 1:1000, ICC: 1:500 up to 1:1000,

Comment:

WB: Antibody 3 is recommended.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50µl H2O to get a 1mg/ml solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C

Storage Comment: Reconstitute and aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized.

References

Limbach, Laue, Wang, Hu, Thiede, Hultqvist, Kilimann: "Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 31, pp. E392-401, (2011) (PubMed).

Target Details

Target: Regulating Synaptic Membrane Exocytosis 1 (RIMS1)

Alternative Name: RIM 1

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity